Hesperidin methyl chalcone (HMC) is a semi-synthetic chalcone derivative of hesperidin, produced by alkaline ring-opening 및 methylation of the parent flavanone. This structural modification significantly enhances water solubility 및 bioavailability compared to native hesperidin.
HMC is a key component of 의약품 및 cosmeceutical formulations targeting vascular permeability, edema reduction, 및 microcirculation improvement. It is clinically used in combination with ascorbic acid 및 rutoside for capillary fragility 및 bruising. Commercially, HMC is applied in vein health 의약품s, under-eye dark circle treatments, 및 cosmeceutical products.