Hordenine HCl is a phenethylamine compound naturally found in barley (Hordeum vulgare), bitter orange (Citrus aurantium), and several other plant species. It appears as an off-white to white crystalline powder with a molecular formula of C10H15NO.HCl and a molecular weight of 201.69. The compound is used primarily as a pharmaceutical intermediate and as an additive in health supplement formulations.
For manufacturers who need kosher-compliant ingredients, verifying the kosher status of hordenine HCl requires reviewing both the raw material source and the production facility certifications. Not all hordenine suppliers carry kosher documentation, so careful supplier selection is important.
Kosher Certification for Hordenine HCl
Hordenine HCl can be produced from natural plant extraction or through synthetic laboratory processes. In either case, kosher certification depends on the full production chain, including solvents, processing aids, and equipment used during manufacturing.
Several established suppliers of hordenine HCl hold both kosher and halal certifications alongside food safety credentials such as ISO9001, ISO22000, HACCP, and FSSC22000. Buyers should request current kosher certificates that name the specific production facility and product specification covered.
Pharmacological Profile and Applications
Hordenine HCl has documented pharmacological effects, including relaxation of bronchial smooth muscle, vasoconstriction, and blood pressure elevation. It has been studied for relieving bronchitis and bronchial asthma symptoms, though most research has been conducted in animal models.
The compound is structurally similar to other phenethylamines such as N-methyltyramine and synephrine, and it shares structural features with ephedrine. Standard commercial specifications call for 98% purity, with microbial testing including total plate count below 1000 CFU/g and yeast and mold below 100 CFU/g.
Regulatory Considerations in the United States
The U.S. FDA has classified hordenine as a new dietary ingredient (NDI) for which a required notification has not been submitted. Products containing hordenine are therefore considered adulterated under current FDA guidelines. The compound also appears on the Department of Defense Prohibited Dietary Supplement Ingredients list and the NCAA banned substances list.
These regulatory factors do not affect the kosher status of the raw material itself, but they are critical for manufacturers to consider when formulating finished products for the U.S. market. Buyers should consult regulatory counsel before incorporating hordenine HCl into consumer-facing supplement products.
Sourcing and Quality Documentation
When purchasing kosher hordenine HCl, request the kosher certificate alongside a full certificate of analysis confirming purity, appearance, melting point (178 degrees Celsius), and microbial safety. Reputable suppliers maintain lot traceability and can provide documentation within 24 hours of inquiry.
The minimum order quantity from most bulk suppliers starts at 500 kg. Storage conditions require a cool, dry environment away from strong light and heat, with a typical shelf life of 36 months under proper conditions.
Kosher Hordenine HCl Supplier
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