Cat's claw extract is obtained from the inner bark of Uncaria tomentosa, a woody vine native to the Amazon rainforest. Extraction uses water or hydroethanolic methods to concentrate the bioactive oxindole alkaloids, including isopteropodine, pteropodine, and mitraphylline.
These alkaloids demonstrate immunomodulatory, anti-inflammatory, and antioxidant properties. Cat's claw extract also contains quinovic acid glycosides and proanthocyanidins that support joint comfort and digestive health. It is commercially used in immune support supplements, joint health formulations, and traditional herbal medicine products.