Applications and Uses of Nisin

Nisin E234 can be used in Food, Beverage, Pharmaceutical, Health & Personal care products, Agriculture/Animal Feed/Poultry. NisinE234 is used as food preservative used in heat-processed foods which includes fresh milk, processed cheese, pasteurized liquid egg, processed meat, seafood, canned food, fruit drinks, vinegar, sauce, soy sauce, protein drinks, and baked products.

Nisin E234 is used to prolong the shelf life by minimizing gram-positive spoilage and pathogenic bacteria. Since Nisin E234 (also known as Streptococcus lactic peptide) is a polypeptide, it is rapidly inactivated in the intestine by digestive enzymes after consumption, Extensive micro-biological tests have not shown any cross resistant between Nisin E234 and medical antibacterial drug. Nisin E234 possesses anti-microbial activity against a wide range of Gram-positive bacteria and their spores which causes food spoilage, and especially inhibits the heat-resistant bacilli, such as B. Stearothermophilus, CI. Butyricum and L. Monocytogenes. It is a natural food preservative which is highly efficient, safe and has no side-effects. In addition, it has excellent solubility and stability in food. It is not effective against Gram-negative bacteria, yeasts or mould.

Nisin E234 uses as follows:

Nisin

In Food

Nisin E234 can be used in a wide range of heat-processed foods. These include: fresh milk, processed cheese and other dairy products, pasteurized liquid egg, processed meat, seafood, canned food, fruit drinks, vinegar, sauce, soy sauce, composite flavorings, plant protein drinks, baked products, instant food, beer, wine etc. It can also be used as a preservative in gelatin processing, cosmetics, drugs and health products.

Product

Ingredient

Max use(g/kg)

Application and use

Nisin

Nisin and NaCl

0.2

Canned food, plant protein drinks

0.5

dairy products

0.5

Cooked meat products, processed meat products

0.15

Coffee drinks, tea drinks, vinegar

0.2

Milk drinks

0.2

Soy sauce, sauce and sauce products

0.2

Compound seasoning

0.25

Other grains (limited to grains enema)

0.25

Instant rice products (limited to rice enema products)

0.15

Instant rice noodles products (limited to wet noodles products)

0.5

Cooked aquatic products (can be consumed directly)

0.25

Egg products (change their physical properties)

……

……

General dosage: 0.03-0.2gram per kilogram food to be processed Nisin E234 dissolve well in low pH condition. You may confect solution with PH3-4 and containing 5% Nisin preparation by adding diluted acetic acid, diluted citric acid or 0.02ml/l HCL first, then put it into the food and mix fully. Or, dilute gradually and add. Sometimes, Nisin E234 can be dissolved directly in the original soup of the food. Nisin E234 can also be used together with other food preservatives.
       

In Beverage

Nisin E234 can be used as preservative in beverage such as in Alcoholic Beverage.

In Pharmaceutical

Nisin E234 can be used as preservative in Pharmaceutical.

In Health and Personal care

Nisin E234 can be used as preservative in Cosmetics.

In Agriculture/Animal Feed/Poultry

NA.

In Other Industries

NA.