L-Lysine is an essential amino acid in the body, aiding in the synthesis of protein. It is most commonly used in beverages, rice, flower and canned goods as a nutritional supplement. Though it’s considered safe, some are convinced it has potentially dangerous health effects.
What Is L-Lysine?
L-Lysine is an amino acid that presents itself as a white crystalline powder that is soluble in water, and almost insoluble in alcohol and ether. With no odor and a bitter taste, it is used as a food preservative and has found application in boiled rice and noodles; custard cream; cooked vegetables and soups; potato salad; sliced fish and sushi; and steamed cakes.
Possible Side Effects of L-Lysine
Although L-Lysine generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:
- stomach pain and diarrhea.
GRAS Affirmation: Yes
Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Lysine is considered safe.
Special Populations Precaution
There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Lysine populations. Better consult to your doctor if you would like to intake L-Lysine.
1. In vivo toxicity and biodistribution of intraperitoneal and intravenous poly-L-lysine and poly-L-lysine/poly-L-glutamate in rats. [J Mater Sci Mater Med. 2014 May] Author: Isaksson K, Akerberg D, Posaric-Bauden M, Andersson R, Tingstedt B.
2. Enhanced epsilon-poly-L-lysine production from Streptomyces ahygroscopicus by a combination of cell immobilization and in situ adsorption. [J Microbiol Biotechnol. 2012 Sep] Author: Liu S, Wu Q, Zhang J, Mo S, Yang X, Xiao C
3. In vivo distribution of avidin-conjugated MX35 and (211)At-labeled, biotinylated poly-L-lysine for pretargeted intraperitoneal α-radioimmunotherapy. [Cancer Biother Radiopharm. 2011 Dec] Author: Frost SH, Bäck T, Chouin N, Jensen H, Hultborn R, Jacobsson L, Lindegren S.
4. Study on galactose-poly(ethylene glycol)-poly(L-lysine) as novel gene vector for targeting hepatocytes in vitro. [J Biomater Sci Polym Ed. 2012] Author: Hu HM, Zhang X, Zhong NQ, Pan SR.
5. Isolation and characterization of a novel ε-poly-L-lysine producing strain: Streptomyces griseofuscus. [J Ind Microbiol Biotechnol. 2011 Apr] Author: Li S, Tang L, Chen X, Liao L, Li F, Mao Z.