L-Lysine Monohydrochloride Side Effects

L-Lysine Monohydrochloride is one of the important compositions of protein. It used as an enhancing agent to rice and flour, and it may also be an efficient dietary supplement providing health benefits like improving growth, adjusting appetite, reducing diseases, and making the body stronger. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Lysine Monohydrochloride?

L-Lysine Monohydrochloride is a branched-chain amino acid. The human body cannot synthesize L-Leucine therefore, it must be ingested. It helps preserve lean muscle tissue, it supplies the body with energy when under stress, it preserves muscle glycogen, it maintains nitrogen balance, and it enhances thinking abilities that can decline as physical activity becomes more intense. It also works to heal bone, skin and muscle tissue and is commonly used as a treatment for cold sores.

Possible Side Effects of L-Lysine Monohydrochloride

Although L-Lysine Monohydrochloride generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • 1. Allergic Reactions

    An excessive intake of lysine causes allergic reactions. Although the allergies differ from person to person, patients will often experience swellings around the face, lips and tongue. It also causes blocking of the throat, and difficulties in breathing.

    2. Interaction with Antibiotics

    Lysine is not to be mixed with other drugs unless recommended by a doctor. Antibiotics such as gentamicin, tobracin, netilmicin, neomycin, amikacin, kanamycin, streptomycin and tobramycin react with lysine causing adverse effects. These can cause body toxins and can be lethal. It is important to take the supplements under strict medical guidance.

    3. Causing Health Disorders

    The over consumption of lysine prevents proper blood circulation, and it hardens the arteries. This can cause serious medical conditions like heart attack, cardiovascular complications and stroke. Lysine is responsible for hardening of arteries; it also causes stomach cramps, diarrhea and gall stones. Anyone with any medical conditions needs to seek medical advice before using lysine. It is forbidden for people with heart, kidney, and liver conditions. Expectant women and nursing mothers are also cautioned against taking lysine since its negative effects are unclear.

    4. Heavy Metals

    These amino acids have been found to contain heavy metals, which are harmful to your health. These can cause death as a result of poisoning. Since there is no regulatory standard against the manufacture of lysine, caution should be taken when using it. In case of an overdose, immediate medical treatment should be sought.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Lysine Monohydrochloride is considered safe.

Suggested Dosage


Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Lysine Monohydrochloride populations. Better consult to your doctor if you would like to intake L-Lysine Monohydrochloride.




Related Research

1. Studies on the effect of polymer coating on solution grown hygroscopic non-linear optical single crystal of L-lysine monohydrochloride. [Spectrochim Acta A Mol Biomol Spectrosc. 2012 Nov] Author: Rani N, Vijayan N, Maurya KK, Haranath D, Saini P, Rathi B, Wahab MA, Bhagavanarayana G.

2. Effects of L-lysine monohydrochloride on insulin and blood glucose levels in spinal cord injured rats. [Chin Med J (Engl). 2010 Mar 20] Author: Zhang TL, Zhao YW, Liu XY, Ding SJ.

3. Probes on L-lysine monohydrochloride dihydrate: a semiorganic nonlinear optical crystal. [Spectrochim Acta A Mol Biomol Spectrosc. 2008 Nov 15] Author: Krishnakumar V, Nagalakshmi R, Manohar S, Kocsis L.

4. Plasticity and slip system of plate-shaped crystals of L-lysine monohydrochloride dihydrate. [Pharm Res. 2002 Apr] Author: Bandyopadhya R, Grant DJ.

5. Influence of crystal shape on the tableting performance of L-lysine monohydrochloride dihydrate. [J Pharm Sci. 2001 May] Author: Sun C, Grant DJ.

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