Sodium Bicarbonate Side Effects

Sodium Bicarbonate E500 is a chemical compound with the formula NaHCO3. It is a salt composed of sodium ions and bicarbonate ions. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Sodium Bicarbonate E500?

Sodium Bicarbonate E500, known as baking soda, is a chemical leavening agent. This product appears as a white powder with a salty aroma. It reacts with acidic components in batters, releasing carbon dioxide which causes expansion in the batter and forms grainy texture in applications like pancakes, quick bread or fried foods.

Possible Side Effects of Sodium Bicarbonate E500

Sodium Bicarbonate E500 is generally considered a safe ingredient. The side effects may:

  • Frequent urge to urinate
  • headache (continuing)
  • loss of appetite (continuing)
  • mood or mental changes
  • muscle pain or twitching
  • nausea or vomiting
  • nervousness or restlessness
  • slow breathing
  • swelling of feet or lower legs
  • unpleasant taste
  • unusual tiredness or weakness

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Sodium Bicarbonate E500 is considered safe by FDA.

Suggested Dosage


Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Sodium Bicarbonate populations. Better consult to your doctor if you would like to intake Sodium Bicarbonate.

Related Research

1. Sodium acetate as a replacement for sodium bicarbonate in medical toxicology: a review. [J Med Toxicol. 2013 Sep] Author: Neavyn MJ, Boyer EW, Bird SB, Babu KM.

2. Oral prostaglandin e1 in combination with sodium bicarbonate and normal saline in the prevention of contrast-induced nephropathy: a pilot study. [Int J Angiol. 2011 Dec] Author: Franz RW, Hinze SS, Knapp ED, Jenkins JJ 2nd.

3. Effects of caffeine, sodium bicarbonate, and their combined ingestion on high-intensity cycling performance. [Int J Sport Nutr Exerc Metab. 2012 Jun] Author: Kilding AE, Overton C, Gleave J.

4. Dimethyl sulfoxide and sodium bicarbonate in the treatment of refractory cancer pain. [J Pain Palliat Care Pharmacother. 2011] Author: Hoang BX, Tran DM, Tran HQ, Nguyen PT, Pham TD, Dang HV, Ha TV, Tran HD, Hoang C, Luong KN, Shaw DG.

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