Disodium 5'-Ribonucleotides Side Effects

Disodium 5′-ribonucleotides, E number E635, is a flavor enhancer which is synergistic with glutamates in creating the taste of umami. It is a mixture of disodium inosinate (IMP) and disodium guanylate (GMP) and is often used where a food already contains natural glutamates (as in meat extract) or added monosodium glutamate (MSG). Though Disodium 5′-ribonucleotides E635 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Disodium 5′-Ribonucleotides E635?

Disodium 5′-Ribonucleotides(I+G) is a flavor enhancer which is synergistic with glutamates in creating the taste of umami. It is a mixture of disodium Inosinate (IMP) and disodium guanylate (GMP) and is often used where a food already contains natural glutamates (as in meat extract) or added Monosodium Glutamate (MSG). It is primarily used in flavored noodles, snack foods, chips, crackers, sauces and fast foods.

Possible Side Effects of Disodium 5′-Ribonucleotides E635

Disodium 5′-Ribonucleotides is generally considered a safe ingredient.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Disodium 5′-Ribonucleotides E635 is considered safe by FDA.

Suggested Dosage


Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Disodium 5′-Ribonucleotides populations. Better consult to your doctor if you would like to intake Disodium 5′-Ribonucleotides.


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