Pectin Side Effects

Pectin is a structural heteropolysaccharide contained in the primary cell walls of terrestrial plants. It is produced commercially as a white to light brown powder, mainly extracted from citrus fruits, and is used in food as a gelling agent, particularly in jams and jellies. It is also used in dessert fillings, medicines, sweets, as a stabilizer in fruit juices and milk drinks, and as a source of dietary fiber. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Pectin?

High Methoxyl Pectin are composed of more than 50% of esterified galacturonic acid units. We offer a broad range of different DE from 50% to 78%. HM pectins are standardised either to specific setting temperatures, viscosities, calcium reactivity, protein stabilising capacity or specific buffer capacity.

Low Methoxyl Pectin are composed of less than 50% of esterified galacturonic acid units. DE typically ranges from 30% to 48%. We offer a broad range of LM pectins with different calcium sensitivities. Gel formation of LM pectin occurs in the presence of calcium ions or similar cations within a wide range of pH values at soluble solids levels below 50%. Lower DE generally increases the calcium reactivity and less cations are needed for optimal gel formation.

Possible Side Effects of Pectin

Although Pectin generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • Bloating 


    Decrease in Appetite

    Mineral Depletion

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Pectin is considered safe.

Suggested Dosage


Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Pectin populations. Better consult to your doctor if you would like to intake Pectin.




Related Research

1. Pharmacokinetics and relative bioavailability of fentanyl pectin nasal spray 100 – 800 µg in healthy volunteers. [Int J Clin Pharmacol Ther. 2010 Dec] Author: Fisher A, Watling M, Smith A, Knight A.

2. Long-term safety, tolerability, and consistency of effect of fentanyl pectin nasal spray for breakthrough cancer pain in opioid-tolerant patients. [J Opioid Manag. 2010 Sep-Oct] Author: Portenoy RK, Raffaeli W, Torres LM, Sitte T, Deka AC, Herrera IG, Wallace MS; Fentanyl Nasal Spray Study 045 Investigators Group.

3. Safety evaluation of pectin-derived acidic oligosaccharides (pAOS): genotoxicity and sub-chronic studies. [Regul Toxicol Pharmacol. 2010 Jun] Author: Garthoff JA, Heemskerk S, Hempenius RA, Lina BA, Krul CA, Koeman JH, Speijers GJ.

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