D-Ribose Side Effects

Ribose is a carbohydrate with the formula C5H10O5; specifically, it is a pentosemonosaccharide (simple sugar) with linear form H−(C=O)−(CHOH)4−H, which has all the hydroxyl groups on the same side in the Fischer projection. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is D-Ribose?

D-Ribose is a white or slightly yellow crystalline powder. It is a pentose monosaccharide or simply known as a simple sugar. This product is known to generate and recover ATP levels and can be used to promote a healthy heart and help the body muscles recover more quickly after exercise. It can be found in health foods and other supplements.

Possible Side Effects of D-Ribose

Although D-Ribose generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • D-Ribose can cause stomach discomfort such as diarrhea, stomach pain and nausea.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. D-Ribose is considered safe.

Suggested Dosage


Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to D-Ribose populations. Better consult to your doctor if you would like to intake D-Ribose.



Related Research

1. Evaluation of D-ribose pharmacokinetics, dose proportionality, food effect, and pharmacodynamics after oral solution administration in healthy male and female subjects. [J Clin Pharmacol. 2013 Nov 23] Author: Thompson J, Neutel J, Homer K, Tempero K, Shah A, Khankari R.

2. Evaluation of α-D-ribofuranose (D-ribose) toxicity after intravenous administration to rabbits. [Hum Exp Toxicol. 2012 Aug] Author: Ismail ZB, Abu-Baker N, Alzoubi K, Al-Zhgoul M, Al-Essa MK, Khlouf S, Al-Saleh A, Al-Omari B, Abu-Tayeh R, Shomaf M, Battah A, Al-Hadidi K.

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