Succinic Acid Side Effects

Succinic acid E363 is a dicarboxylic acid with the chemical formula (CH2)2(CO2H)2. Though Succinic acid E363 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Succinic Acid E363?

As a food additive and dietary supplement, succinic acid is generally recognized as safe by the U.S. Food and Drug Administration. Succinic acid E363 is used primarily as an acidity regulator in the food and beverage industry. It is also available as a flavoring agent, contributing a somewhat sour and astringent component to umami taste.

Possible Side Effects of Succinic Acid E363

Although Succinic Acid E363 generally regarded as a very safe and effective supplement, there can be some minor side effects. Possible side effects: Constipation; darkened stools; diarrhea; mild stomach pain; nausea; vomiting.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Succinic Acid E363 is considered safe by FDA.

Suggested Dosage


Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Succinic Acid E363 populations. Better consult to your doctor if you would like to intake Succinic Acid E363.




Related Research

1. Conjugation of succinic acid to non-ionogenic amphiphilic polymers modulates their interaction with cell plasma membrane and reduces cytotoxic activity. [Colloids Surf B Biointerfaces. 2013 Sep 1] Author: Bondar OV, Sagitova AV, Badeev YV, Shtyrlin YG, Abdullin TI.

2. 99mTechnetium-dimercapto-succinic acid renal scan in the evaluation of potential long-term renal parenchymal damage associated with extracorporeal shock wave lithotripsy in children. [J Urol. 1998 Feb] Author: Lottmann HB, Archambaud F, Hellal B, Pageyral BM, Cendron M.

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