L-Aspartic Acid Side Effects

L-Aspartic Acid is a white crystal or crystalline powder. It improves biological quality of protein and acts as a nutrient and dietary supplement. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is L-Aspartic Acid?

L-Aspartic Acid, also known as Aspartate, is an amino acid that presents itself as a white odorless powder that is characteristic of an acid-like taste. It is slightly water soluble and insoluble in fat. It is used as a food additive to improve protein content, and can also be used as a flavor enhancer. It has found application as the base of the common sweetener aspartame.

Possible Side Effects of L-Aspartic Acid

Although L-Aspartic Acid generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • Asthma
  • Abdominal pain
  • Gout
  • Bloating
  • Diarrhea
  • Allergies

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Aspartic Acid is considered safe.

Suggested Dosage


Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to L-Aspartic Acid populations. Better consult to your doctor if you would like to intake L-Aspartic Acid.



Related Research

1. Effect of l-aspartic acid on the growth, structure and spectral studies of Zinc (tris) Thiourea Sulphate (ZTS) single crystals. [Spectrochim Acta A Mol Biomol Spectrosc. 2014 Nov 11] Author: Samuel BS, Krishnamurthy R, Rajasekaran R.

2. Synthesis and characterization of novel stimuli-responsive hydrogels based on starch and L-aspartic acid. [Carbohydr Polym. 2013 Nov 6] Author: Vakili MR, Rahneshin N.

3. Molecularly imprinted polymer-matrix nanocomposite for enantioselective electrochemical sensing of D- and L-aspartic acid. [Mater Sci Eng C Mater Biol Appl. 2013 Oct] Author: Prasad BB, Srivastava A, Tiwari MP.

4. Amphiphilic poly(L-aspartic acid) copolymer nanoparticles for cyclosporine A delivery. [J Nanosci Nanotechnol. 2013 Feb] Author: Han S, Sun Y, Su S, Hu L, Wu Y.

5. Biodegradable and redox-responsive chitosan/poly(L-aspartic acid) submicron capsules for transmucosal delivery of proteins and peptides. [J Mater Sci Mater Med. 2013 Apr] Author: Zheng C, Zhang XG, Sun L, Zhang ZP, Li CX.