Propylene Glycol Side Effects

Propylene Glycol E1520 is a colorless, nearly odorless, clear, viscous liquid with a faintly sweet taste. It is used as as an emulsifier, humectant, and solvent and in multiple other applications. Propylene Glycol E1520 is commonly used as a humectant and food preservative. Though Propylene Glycol E1520 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Propylene Glycol E1520?

Propylene Glycol (PG) E1520 is a versatile product used in a variety of applications. For industrial use, propylene glycol E1520 is a chemical feedstock for the production of unsaturated polyester resins, and it can also be used for anti-freeze purposes or as a de-icer. Uses for USP grade Propylene Glycol include use as a solvent in pharmaceutical products and use as a humectant and emulsifier in the production of food and personal care products and in liquid laundry detergents.

Possible Side Effects of Propylene Glycol E1520

Although Propylene Glycol E1520 generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • temporarily blurry vision, irritation, stinging and minor burning. Some of the more serious side effects include eye pain, altered vision and ongoing irritation in the eyes.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Propylene Glycol E1520 is considered safe.

Suggested Dosage


Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Propylene Glycol E1520 populations. Better consult to your doctor if you would like to intake Propylene Glycol E1520.




Related Research

1. Propylene-Glycol Aggravates LPS-Induced Sepsis through Production of TNF-α and IL-6. [Iran J Immunol. 2014 Jun] Author: Marton A, Kolozsi C, Kusz E, Olah Z, Letoha T, Vizler C, Pecze L.

2. Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics. [Int J Toxicol. 2012 Sep-Oct] Author: Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler D, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Andersen FA.

3. Evaluation of the effect of green tea extract on mouth bacterial activity in the presence of propylene glycol. [Jundishapur J Nat Pharm Prod. 2012 Spring] Author: Moghbel A, Farjzadeh A, Aghel N, Agheli H, Raisi N.

4. Propylene glycol produces excessive apoptosis in the developing mouse brain, alone and in combination with phenobarbital. [Pediatr Res. 2012 Jan] Author: Lau K, Swiney BS, Reeves N, Noguchi KK, Farber NB.

5. Prospective assessment of short-term propylene glycol tolerance in neonates. [Arch Dis Child. 2010 Dec] Author: Allegaert K, Vanhaesebrouck S, Kulo A, Cosaert K, Verbesselt R, Debeer A, de Hoon J.

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