Vitamin K1 Side Effects

Vitamin K1 is a pale yellow to golden yellow transparent oily liquid or powder. It has applications as a nutritional enhancer for milk powder, biscuits, and other food. Also, it can be used as pharmaceutical raw materials that play a role in hemostasis but also can be used for multi-dimensional food and livestock feed additives. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Vitamin K1?

Vitamin K1 appears as a fine white to off-white colored powder. It is found naturally in a wide variety of green plants, particularly leaves. Vitamin K is a group of structurally similar, fat-soluble vitamins that are needed for the post transitional modification of certain proteins required for blood coagulation and in metabolic pathways in bone and other tissue. This product is often used as a dietary supplement.

Possible Side Effects of Vitamin K1

Vitamin K1 is generally considered a safe ingredient. Common side effects of Vitamin K1 includedizziness, sweating, and injection site reactions (pain, swelling, and tenderness), temporary flushing, taste changes, rapid heartbeat, shortness of breath, or bluishlips/skin/nails.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Vitamin K1 is considered safe by FDA.

Suggested Dosage


Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Vitamin K1 populations. Better consult to your doctor if you would like to intake Vitamin K1.



Related Research

1. Vitamin K1 to slow vascular calcification in haemodialysis patients (VitaVasK trial): a rationale and study protocol. [Nephrol Dial Transplant. 2014 Sep] Author: Krueger T, Schlieper G, Schurgers L, Cornelis T, Cozzolino M, Jacobi J, Jadoul M, Ketteler M, Rump LC, Stenvinkel P, Westenfeld R, Wiecek A, Reinartz S, Hilgers RD, Floege J.

2. Efficacy and safety of intravenous phytonadione (vitamin K1) in patients on long-term oral anticoagulant therapy. [Mayo Clin Proc. 2001 Mar] Author: Shields RC, McBane RD, Kuiper JD, Li H, Heit JA.

3. Low-dose vitamin K1 versus short-term with holding of acenocoumarol in the treatment of excessive anticoagulation episodes induced by acenocoumarol. A retrospective comparative study. [Haemostasis. 1998 Mar-Apr] Author: Ortín M, Olalla J, Marco F, Velasco N.

4. Intravenous versus subcutaneous vitamin K1 in reversing excessive oral anticoagulation. [Am J Cardiol. 1999 Jan 15] Author: Nee R, Doppenschmidt D, Donovan DJ, Andrews TC.

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