Calcium Acetate Monohydrate Side Effects

Calcium Acetate Monohydrate Side Effects

Calcium Acetate Monohydrate is a food perservative used widely in food and beverage. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Calcium Acetate Monohydrate?

Calcium Acetate Monohydrate, also known as calcium acetate, is a white, odorless, and tasteless crystalline powder. Calcium Acetate Monohydrate is used in the food and beverage industry as a food additive, stabilizer, buffer, and sequestrant. Calcium Acetate Monohydrate is mainly used in the production of candy products, desserts, and baked good (bread, cakes, pastries). 

Possible Side Effects of Calcium Acetate Monohydrate

Common side effect of Calcium Acetate Monohydrate as follows:

  • Abdominal or stomach pain
  • confusion
  • constipation
  • depression
  • dry mouth
  • full or partial loss of consciousness
  • headache
  • incoherent speech
  • increased urination
  • loss of appetite
  • metallic taste
  • muscle weakness
  • nausea or vomiting
  • thirst
  • unusual tiredness
  • weight loss

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Calcium Acetate Monohydrate Side Effects is on FDA’s GRAS exemption list, it’s still widely accepted as safe food additive in many countries including USA with specific limit on dosage.

Suggested Dosage


Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Calcium Acetate Monohydrate populations. There is no evidence that Calcium Acetate Monohydrate could have any negative effects on these population.


Related Research

1. Effect of lanthanum carbonate and calcium acetate in the treatment of hyperphosphatemia in patients of chronic kidney disease. [Indian J Pharmacol. 2009 Aug] Author: Scaria PT, Gangadhar R, Pisharody R.

2. Comparative effectiveness of calcium acetate and sevelamer on clinical outcomes in elderly hemodialysis patients enrolled in medicare part d. [Am J Kidney Dis. 2014 Jul] Author: Yusuf AA, Weinhandl ED, St Peter WL.

3. A comparison of calcium acetate/magnesium carbonate and sevelamer-hydrochloride effects on fibroblast growth factor-23 and bone markers: post hoc evaluation from a controlled, randomized study. [Nephrol Dial Transplant. 2013 Sep] Author: Covic A, Passlick-Deetjen J, Kroczak M, Büschges-Seraphin B, Ghenu A, Ponce P, Marzell B, de Francisco AL.

4. Comparison of calcium acetate and sevelamer on vascular function and fibroblast growth factor 23 in CKD patients: a randomized clinical trial. [Am J Kidney Dis. 2012 Feb] Author: Yilmaz MI, Sonmez A, Saglam M, Yaman H, Kilic S, Eyileten T, Caglar K, Oguz Y, Vural A, Yenicesu M, Mallamaci F, Zoccali C.

5. Efficacy and safety of sevelamer hydrochloride and calcium acetate in patients on peritoneal dialysis [Nephrol Dial Transplant. 2009 Jan] Author: Evenepoel P, Selgas R, Caputo F, Foggensteiner L, Heaf JG, Ortiz A, Kelly A, Chasan-Taber S, Duggal A, Fan S.

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