Disodium EDTA E386 can be used when there is a chelating agent needed for general use and in food processing. Though Disodium EDTA E386 is considered safe, some are convinced it has potentially dangerous health effects.
What Is Disodium EDTA E386?
EDTA stands for ethylenediaminetetraacetic acid, chemical formula C10H16N2O8. It is primarily synthesised from ethylenediamine, formaldehyde and sodium cyanide. Disodium EDTA E386 is a salt produced during this synthesis. Disodium EDTA E386 is used as a food additive in products like chicken nuggets, marshmallows, pudding, caned tuna and others. It is used as a palatability enhancer.
Possible Side Effects of Disodium EDTA E386
Disodium EDTA E386 side effects may abdominal cramps, nausea, vomiting, diarrhea, headache, low blood pressure, skin problems, and fever.
GRAS Affirmation: No
Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Disodium EDTA E386 is considered safe by FDA.
Special Populations Precaution
There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Disodium EDTA E386 populations. Better consult to your doctor if you would like to intake Disodium EDTA E386.
1. Effectiveness of treatment of calcific tendinitis of the shoulder by disodium EDTA. [Arthritis Rheum. 2009 Jan 15] Author: Cacchio A, De Blasis E, Desiati P, Spacca G, Santilli V, De Paulis F.
2. High-purity nano particles ZnS production by a simple coupling reaction process of biological reduction and chemical precipitation mediated with EDTA. [Biotechnol Prog. 2008 Sep-Oct] Author: Xin B, Huang Q, Chen S, Tang X.
3. Effect of ovotransferrin, protamine sulfate and EDTA combination on biofilm formation by catheter-associated bacteria. [J Appl Microbiol. 2007 Mar] Author: Yakandawala N, Gawande PV, Lovetri K, Madhyastha S.
4. The effect of clodronate on the integrity and viability of rat small intestine in vitro-a comparison with EDTA. [Biol Pharm Bull. 2005 Jul] Author: Zakelj S, Vadnjal L, Kristl A.