EDTA Side Effects

EDTA also known as Ethylenediaminetetraacetic acid, is a chemical used for both industrial and medical purposes. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is EDTA?

EDTA can be used as a chelating agent; preservative, flavoring and stabilizing agent, as well as a color retention agent in foods.

Possible Side Effects of EDTA

EDTA side effects may such as nausea and vomiting, as well as a headache.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. EDTA is considered safe by FDA.

Suggested Dosage


Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to EDTA populations. Better consult to your doctor if you would like to intake EDTA.


Related Research

1. Effectiveness of treatment of calcific tendinitis of the shoulder by disodium EDTA. [Arthritis Rheum. 2009 Jan 15] Author: Cacchio A, De Blasis E, Desiati P, Spacca G, Santilli V, De Paulis F.

2. High-purity nano particles ZnS production by a simple coupling reaction process of biological reduction and chemical precipitation mediated with EDTA. [Biotechnol Prog. 2008 Sep-Oct] Author: Xin B, Huang Q, Chen S, Tang X.

3. Effect of ovotransferrin, protamine sulfate and EDTA combination on biofilm formation by catheter-associated bacteria. [J Appl Microbiol. 2007 Mar] Author: Yakandawala N, Gawande PV, Lovetri K, Madhyastha S.

4. The effect of clodronate on the integrity and viability of rat small intestine in vitro-a comparison with EDTA. [Biol Pharm Bull. 2005 Jul] Author: Zakelj S, Vadnjal L, Kristl A.

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