Ascorbyl Palmitate Side Effects

Ascorbyl Palmitate E304 (also known as Vitamin C Ester) is a non-acidic form of Vitamin C. It is made from Ascorbic Acid (Vitamin C) and Palmitic Acid (a fatty acid). Ascorbyl Palmitate E304 is widely used in food and beverage products, including breads, crackers and cookies.Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Ascorbyl Palmitate E304?

Ascorbyl Palmitate E304 is an effective antioxidant: it helps fight free radicals and boost collagen synthesis. It is more stable than L-ascorbic acid (pure Vitamin C) and non-irritating. Because it is fat-soluble, it penetrates the skin readily and easily, delivering its benefits efficiently.
In addition, Asorbyl Palmitate E304 can also be used as a preservative in both beauty products and food to prevent them from going bad.

Possible Side Effects of Ascorbyl Palmitate E304

Ascorbyl Palmitate E304 is generally considered a safe ingredient. Although one study indicated that ascorbyl palmitate may be potentially carcinogenic, many other studies have shown that it is not mutagenic, inhibits tumour promotion on mouse skin and exerts cytotoxic effects on cancer cells.

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Ascorbyl Palmitate E304 is considered safe by FDA.

Suggested Dosage


Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Ascorbyl Palmitate E304 populations. Better consult to your doctor if you would like to intake Ascorbyl Palmitate E304.



Related Research

1. Molecular encapsulation of ascorbyl palmitate in preformed V-type starch and amylose. [Carbohydr Polym. 2014 Oct 13] Author: Kong L, Ziegler GR.

2. Protective effects of equimolar mixtures of monomer and dimer of dehydrozingerone with α-tocopherol and/or ascorbyl palmitate during bulk lipid autoxidation. [Food Chem. 2014 Aug 15] Author: Kancheva V, Slavova-Kazakova A, Fabbri D, Dettori MA, Delogu G, Janiak M, Amarowicz R.

3. Study of the influence of ascorbyl palmitate and amiodarone in the stability of unilamellar liposomes. [Mol Membr Biol. 2014 Mar-May] Author: Benedini L, Antollini S, Fanani ML, Palma S, Messina P, Schulz P.

4. Ascorbyl palmitate/DSPE-PEG nanocarriers for oral iron delivery: preparation, characterisation and in vitro evaluation. [Colloids Surf B Biointerfaces. 2014 Mar 1] Author: Zariwala MG, Farnaud S, Merchant Z, Somavarapu S, Renshaw D.

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