Vitamin B2 Side Effects

Vitamin B2, also called riboflavin, is one of 8 B vitamins. All B vitamins help the body to convert food (carbohydrates) into fuel (glucose), which is used to produce energy.  VitaminB2 is used in wheat flour, dairy products, soy sauce, rice, breads, biscuits, chocolates, and other foods and beverages. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Vitamin B2 (Riboflavin)?

Vitamin B2 (Riboflavin) appears as a yellow to orange crystalline powder. It is one of the thirteen necessary vitamins for human body and a member of vitamin B group. This product is often used as a fortifier in baby foods, breakfast cereals, pastas, sauces, processed cheese, fruit drinks, vitamin-enriched milk products, and some energy drinks.

Possible Side Effects of Vitamin B2 (Riboflavin)

Although Vitamin B2 (Riboflavin) generally regarded as a very safe and effective supplement, there can be some minor side effects. The side effects may:

  • Very high doses may cause:
    • Itching
    • Numbness
    • Burning or prickling sensations
    • Yellow or orange urine
    • Sensitivity to light

GRAS Affirmation: Yes

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Vitamin B2 (Riboflavin) is considered safe.

Suggested Dosage


Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Vitamin B2 (Riboflavin)populations. Better consult to your doctor if you would like to intake Vitamin B2 (Riboflavin).




Related Research

1. Vitamin B2 in nanoscopic environments under visible light: photosensitized antioxidant or phototoxic drug? [J Phys Chem A. 2014 Jun 5] Author: Chaudhuri S, Batabyal S, Polley N, Pal SK.

2. Riboflavin (vitamin B2) and oxidative stress: a review. [Br J Nutr. 2014 Mar 20] Author: Ashoori M, Saedisomeolia A.

3. Riboflavin (vitamin B2 ) deficiency impairs NADPH oxidase 2 (Nox2) priming and defense against Listeria monocytogenes. [Eur J Immunol. 2014 Mar] Author: Schramm M, Wiegmann K, Schramm S, Gluschko A, Herb M, Utermöhlen O, Krönke M.

4. Effect of pH(24h), curing salts and muscle types on the oxidative stability, free amino acids profile and vitamin B2, B3 and B6 content of dry-cured ham. [Food Chem. 2013 Dec 1] Author: Gratacós-Cubarsí M, Sárraga C, Castellari M, Valero A, García Regueiro JA, Arnau J.

5. Fluorescence resonance energy transfer from sulfonated graphene to riboflavin: a simple way to detect vitamin B2. [ACS Appl Mater Interfaces. 2013 Aug 14] Author: Kundu A, Nandi S, Layek RK, Nandi AK.

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