Polysorbate 20 Side Effects

Polysorbate 20 E432 is a polysorbate-type nonionic surfactant formed by the ethoxylation of sorbitan before the addition of lauric acid. Though Polysorbate 20 E432 is considered safe, some are convinced it has potentially dangerous health effects.

What Is Polysorbate 20 E432?

Polysorbate 20 E432 is a yellow to amber liquid with a faint odor and a warm, somewhat bitter taste. This product is a mixture of laurate, partial esters of sorbitol, and sorbitol anhydrides condensed with 20moles of ethylene oxide. It is commonly used as a wetting agent in flavored mouth drops to spread the feeling of other ingredients such as mint flavor, but it can also be used in food as a flavoring ingredient.

Possible Side Effects of Polysorbate 20 E432

Polysorbate 20 E432 is generally recognised safe. The possible side-effects that may: Eye irritation

GRAS Affirmation: No

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Polysorbate 20 E432 is considered safe.

Suggested Dosage

NA.

Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Genistein populations. Better consult to your doctor if you would like to intake Polysorbate 20.

Related Research

1. The effects of membrane filters used in biopharmaceutical processes on the concentration and composition of polysorbate 20. [Biotechnol Prog. 2013 Nov-Dec] Author: Lei M, Hewitt D, Cornell C, Skidmore K, Kao YH, Sugahara J, Beane D, Ji J.

2. Characterization and stability study of polysorbate 20 in therapeutic monoclonal antibody formulation by multidimensional ultrahigh-performance liquid chromatography-charged aerosol detection-mass spectrometry. [Anal Chem. 2014 May 20] Author: Li Y, Hewitt D, Lentz YK, Ji JA, Zhang TY, Zhang K.

3. The effects of membrane filters used in biopharmaceutical processes on the concentration and composition of polysorbate 20. [Biotechnol Prog. 2013 Nov-Dec] Author: Lei M, Hewitt D, Cornell C, Skidmore K, Kao YH, Sugahara J, Beane D, Ji J.

4. Alcohols Effect on Critic Micelle Concentration of Polysorbate 20 and Cetyl Trimethyl Ammonium Bromine Mixed Solutions. [J Surfactants Deterg. 2013 Jul] Author: Sidim T, Acar G.