Polysorbate 80 Side Effects

Polysorbate 80 E433 also known as Tween 80.It is an amber/golden-colored viscous liquid. It is made from polyethoxylated sorbitan (chemical compounds derived from the dehydration of sugar alcohol) and oleic acid, a fatty acid found in animal and vegetable fats. Though it’s considered safe, some are convinced it has potentially dangerous health effects.

What Is Polysorbate 80 E433?

Polysorbate 80 E433 is a colorless to yellow liquid used as an emulsifier in foods. It is used in ice cream to make it smoother, easier to handle, and to increase its resistance to melting.

Possible Side Effects of Polysorbate 80 E433

Polysorbate 80 E433 is generally recognised as safe, the side effect may Cough; mild pain at the injection site; mild stomach pain..

GRAS Affirmation: No

Generally recognized as safe (GRAS) is an American Food and Drug Administration (FDA) designation that a chemical or substance added to food is considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Polysorbate 80 E433 is considered safe.

Suggested Dosage


Special Populations Precaution

There is a lot of concern about diet and nutrition for these population, like Newborns, children, pregnant, sensitive to Polysorbate 80 populations. Better consult to your doctor if you would like to intake Polysorbate 80 E433.


Related Research

1. [Advance of polysorbate 80 for injection accessories]. [Zhongguo Zhong Yao Za Zhi. 2011 Jul] Author: Zhang M.

2. Development of Polysorbate 80/Phospholipid mixed micellar formation for docetaxel and assessment of its in vivo distribution in animal models. [Nanoscale Res Lett. 2011 Apr 20] Author: Song H, Geng H, Ruan J, Wang K, Bao C, Wang J, Peng X, Zhang X, Cui D.

3. Polysorbate 80 inhibition of Pseudomonas aeruginosa biofilm formation and its cleavage by the secreted lipase LipA. [Antimicrob Agents Chemother. 2009 Jan] Author: Toutain-Kidd CM, Kadivar SC, Bramante CT, Bobin SA, Zegans ME.

4. Permeabilisation and solubilisation of soybean phosphatidylcholine bilayer vesicles, as membrane models, by polysorbate, Tween 80. [Eur J Pharm Sci. 2005 Nov] Author: Simões SI, Tapadas JM, Marques CM, Cruz ME, Martins MB, Cevc G.

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